Conjugated Polymer Nanoparticles for Two‐Photon Imaging of Endothelial Cells in a Tissue Model

Abstract

Fabrication and characterization of 8-nm-sized conjugated polymer nanoparticles (CPNs) and two-photon (2P) imaging of CPN labeled endothelial cells in a collagen-gel-based microfluidic device is described. CPNs exhibit super brightness and photostability comparable to quantum dots. The hydrophilicity and non-toxicity of CPNs enable long-term monitoring of cells in a tissue model, supporting CPNs' potential in biological and biomedical applications. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.