Efficacy of Small Doses of Ketamine With Morphine to Decrease Procedural Pain Responses During Open Wound Care

Abstract

Ketamine with morphine significantly reduced procedural wound pain intensity during WCP. Adverse effects and higher diastolic BP occurred with MK. Further research is warranted to determine the optimal analgesic dose of ketamine or if the addition of a benzodiazepine would mitigate the psychotomimetic effects of ketamine.