Sarpogrelate Hydrochloride, a 5-HT2A Receptor Antagonist, Attenuates Neurogenic Pain Induced by Nucleus Pulposus in Rats

Abstract

Sarpogrelate attenuated pain-related behavior induced by the nucleus pulposus in the animal model. Although further investigation is needed concerning the mechanism of action, this study supported the hypothesis that sarpogrelate is efficacious for treating the pain of lumbar disc herniation.