The α2-adrenoceptor antagonist activity of ipsapirone and gepirone is mediated by their common metabolite 1-(2-pyrimidinyl)-piperazine (PmP)

STIMULANT ACTIONS OF VOLATILE ANAESTHETICS ON SMOOTH MUSCLE

H P Rang · British Journal of Pharmacology and Chemotherapy · 1964 · 260 citations · Full text

Neurophysiology, Contractile Response, Medicine +15

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Cardiovascular Response to 8-Hydroxy-2-(di-n-Propylamino) Tetralin (8-OH-DPAT) in the Rat: Site of Action and Pharmacological Analysis

John R. Fozard, Anis K. Mir, Derek N. Middlemiss · Journal of Cardiovascular Pharmacology · 1987 · 211 citations

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Serotonergic mechanisms in the behavioral effects of buspirone and gepirone

Arlene S. Eison, Michael S. Eison, Michael Stanley et al. · Pharmacology Biochemistry and Behavior · 1986 · 197 citations

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Brain serotonin receptors as a target for the putative anxiolytic TVX Q 7821

J. Traber, Margaret A. Davies, Wolfgang U. Dompert et al. · Brain Research Bulletin · 1984 · 138 citations

Psychiatry, Neurophysiology, Medicine +12