Concepedia

Publication | Open Access

TB-IRIS After Initiation of Antiretroviral Therapy Is Associated With Expansion of Preexistent Th1 Responses Against Mycobacterium tuberculosis Antigens

DOIFull Paper Access

38

Citations

32

References

2013

Year

Ramachandran Vignesh, Nagalingeswaran Kumarasamy, Andrew Lim, Suniti Solomon, Kailapuri G. Murugavel, Pachamuthu Balakrishnan, Sunil S. Solomon, Kenneth H. Mayer, Chinnambedu Ravichandran Swathirajan, Ezhilarasi Chandrasekaran,
JAIDS Journal of Acquired Immune Deficiency Syndromes

Abstract

TB-IRIS is associated with Th1 responses against M. tuberculosis antigens by CD4⁺ and CD3⁺CD4⁻ T cells that are present before ART and amplified afterward. It is unclear if these cause immunopathology or reflect a high pathogen load.

References

YearCitations

Page 1