Physics in Medicine and Biology · 2008 · 62 citations · 14 references
Natural SciencesPhysicsRadiologyBiomedical ImagingDiagnostic ImagingOpticsLight-tissue InteractionOptical TomographyPhantom DosimetryScattering In TissueScattering TheoryTissue Optical PropertiesColloidal SolutionsDosimetersIn Vivo TomographyLight ScatteringLight-scattering MaterialsOptical Density MeasurementOptical ScatteringOptical Scattering Effects
A gelatin phantom containing an optically scattering funnel-shaped region of elevated optical density (OD) was used to examine light-scattering-induced artefacts in a cone-beam optical CT scanner used for gel dosimetry. To simulate polymer gel dosimeters, the opacity was introduced by adding a colloidal scatterer to the gelatin. Scatter results in an underestimate of OD (hence dose). In line profiles of OD taken from 3D reconstructions of the funnel, those profiles with a long pathlength through high OD regions exhibited a 'dishing' (or 'cupping') artefact, while those of short pathlength exhibited the opposite effect-'doming'. These phenomena are accounted for by a model that includes the effect of stray, scattered light.
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L.A. Feldkamp, L. C. Davis, J. W. Kress · Journal of the Optical Society of America A · 1984 · 6.2K citations
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