Effects of Monoclonal Antibody to P-Selectin and Analogue of Sialyl Lewis X on Cyclic Flow Variations in Stenosed and Endothelium-Injured Canine Coronary Arteries

Takahisa Ueyama, Hisao Ikeda, Nobuya Haramaki, Kazunori Kuwano, Tsutomu Imaizumi

Circulation · 1997 · 30 citations · 38 references

Abstract

These findings indicate that the high dose of SLe(x)-OS and the combination of PB1.3 and the low dose of SLe(x)-OS provide protection against CFVs. Thus, the adhesive interaction between P-selectin and SLe(x) may play an important role in mediating CFVs in this model.

References

38