Concepedia

Ruthenium-catalysed asymmetric hydrogenation of ketones using QUINAPHOS as the ligand

Simon Burk, Giancarlo Franciò, Walter Leitner

Chemical Communications · 2005 · 46 citations · 16 references

DOI

Concepts

Abstract

Highly enantioselective ruthenium-catalysed hydrogenation of aromatic ketones is achieved with (Ra,S(C))-QUINAPHOS in the presence of achiral and chiral diamines as co-catalysts.

References

16

Asymmetric Catalysis by Architectural and Functional Molecular Engineering: Practical Chemo- and Stereoselective Hydrogenation of Ketones

Ryōji Noyori, Takeshi Ohkuma · Angewandte Chemie International Edition · 2001 · 1.9K citations · Full text

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Privileged Chiral Catalysts

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Takeshi Ohkuma, Hirohito Ooka, Shohei Hashiguchi et al. · Journal of the American Chemical Society · 1995 · 719 citations

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Asymmetric Hydrogenation of Alkenyl, Cyclopropyl, and Aryl Ketones. RuCl<sub>2</sub>(xylbinap)(1,2-diamine) as a Precatalyst Exhibiting a Wide Scope

Takeshi Ohkuma, Masatoshi Koizumi, Henri Doucet et al. · Journal of the American Chemical Society · 1998 · 404 citations

, , +15

Synthesis of Spiro Diphosphines and Their Application in Asymmetric Hydrogenation of Ketones

Jian‐Hua Xie, Lixin Wang, Yu Fu et al. · Journal of the American Chemical Society · 2003 · 301 citations

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