Concepedia

KMUP-1 inhibits pulmonary artery proliferation by targeting serotonin receptors/transporter and NO synthase, inactivating RhoA and suppressing AKT/ERK phosphorylation

Hui‐Hsuan Chung, Zen‐Kong Dai, Bin‐Nan Wu, Jwu‐Lai Yeh, Chee‐Yin Chai, Koung‐Shing Chu, Chung-Pin Liu, Ing‐Jun Chen

Vascular Pharmacology · 2010 · 19 citations · 43 references

DOI

Concepts

References

43

Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension

Saadia Eddahibi, Marc Humbert, Élie Fadel et al. · Journal of Clinical Investigation · 2001 · 509 citations · Full text

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Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension

Saadia Eddahibi, Marc Humbert, Élie Fadel et al. · Journal of Clinical Investigation · 2001 · 464 citations

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Long-Term Treatment With a Rho-Kinase Inhibitor Improves Monocrotaline-Induced Fatal Pulmonary Hypertension in Rats

Kohtaro Abe, Hiroaki Shimokawa, Keiko Morikawa et al. · Circulation Research · 2003 · 399 citations

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Upregulated<i>TRP</i>and enhanced capacitative Ca<sup>2+</sup>entry in human pulmonary artery myocytes during proliferation

Vera A. Golovina, Oleksandr Platoshyn, Colleen Bailey et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2001 · 349 citations

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Translocation of rhoA Associated with Ca2+ Sensitization of Smooth Muscle

Ming Gong, Hideyoshi Fujihara, Avril V. Somlyo et al. · Journal of Biological Chemistry · 1997 · 222 citations · Full text

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