Concepedia

Room-Temperature Aromatization of Tetrahydro-β-carbolines by 2-Iodoxybenzoic Acid: Utility in a Total Synthesis of Eudistomin U

Joseph D. Panarese, Stephen P. Waters

Organic Letters · 2010 · 79 citations · 43 references

DOI

Concepts

Abstract

2-Iodoxybenzoic acid is a convenient reagent for the dehydrogenation of tetrahydro-β-carbolines to their aromatic forms under mild conditions. The utility of the method was demonstrated in a total synthesis of the marine indole alkaloid eudistomin U.

References

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Thomas Wirth · Angewandte Chemie International Edition · 2005 · 757 citations

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<i>o</i>-Iodoxybenzoic Acid (IBX) as a Viable Reagent in the Manipulation of Nitrogen- and Sulfur-Containing Substrates:  Scope, Generality, and Mechanism of IBX-Mediated Amine Oxidations and Dithiane Deprotections

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Trichloroisocyanuric Acid:  A Safe and Efficient Oxidant

Ulf Tilstam, Hilmar Weinmann · Organic Process Research & Development · 2002 · 204 citations

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.beta.-Carbolines: synthesis and neurochemical and pharmacological actions on brain benzodiazepine receptors

Michael Cain, Robert Weber, Fil Guzman et al. · Journal of Medicinal Chemistry · 1982 · 178 citations

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