Fanconi's Syndrome and Distal Renal Tubular Acidosis After Glue Sniffing

Abstract

Brief Reports1 January 1980Fanconi's Syndrome and Distal Renal Tubular Acidosis After Glue SniffingALVlN H. MOSS, M.D., PATRICIA A. GABOW, M.D., WILLIAM D. KAEHNY, M.D., STEPHEN I. GOODMAN, M.D., LEWIS L. HAUT, M.D., MARK R. HAUSSLER, Ph.D.ALVlN H. MOSS, M.D., PATRICIA A. GABOW, M.D., WILLIAM D. KAEHNY, M.D., STEPHEN I. GOODMAN, M.D., LEWIS L. HAUT, M.D., MARK R. HAUSSLER, Ph.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-92-1-69 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptGlue, paint, or toluene sniffers may develop signs of renal toxicity including proteinuria, hematuria, and pyuria (1) and distal renal tubular acidosis (2). A glue sniffer with reversible Fanconi's syndrome in addition to distal renal tubular acidosis is described.A 27-year-old woman was hospitalized for evaluation of profound weakness. She reported inhaling glue from a plastic bag daily for 9 months before admission but denied use of drugs or medications. On admission the patient was lethargic, smelled of glue, and had dried glue on her face. Weakness, dysmetria, dysdiadochokinesia, and ataxia were prominent. She had a severe hyperchloremic metabolic acidosis,...References1. HAYDENPETERSONBRUCKNER JRJ. Toxicology of toluene (methylbenzene): review of current literature. Clin Toxicol. 1977;11:549-59. CrossrefMedlineGoogle Scholar2. TAHERANDERSONMCCARTNEYPOPOVTZERSCHRIER SRRMR. Renal tubular acidosis associated with toluene "sniffing." N Engl J Med. 1974;290:765-8. CrossrefMedlineGoogle Scholar3. SOUPART P. Urinary excretion of free amino acids in normal adult men and women. Clin Chem Acta. 1959;4:265-71. CrossrefMedlineGoogle Scholar4. HAUSSLERMCCAIN MT. Basic and clinical concepts related to vitamin D metabolism and action. N Engl J Med. 1977;297:974-83, 1041-50. CrossrefMedlineGoogle Scholar5. WRONGDAVIES OH. The excretion of acid in renal disease. Q J Med. 1959;28:259-313. MedlineGoogle Scholar6. BREWERTSAIMORRIS EHR. Fanconi syndrome and its relationship to vitamin D. In: NORMAN AW, SCHAEFER K, COBURN JW, et al., eds. Vitamin D: Biochemical, Chemical and Clinical Aspects Related to Calcium Metabolism. Proceedings of the Third Workshop on Vitamin D. Berlin: Walter de Gruyter and Co.; 1977:937-49. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByNephrotoxicity of Lithium and Drugs of AbuseTubulointerstitial Injury and Drugs of AbusePediatric Fanconi SyndromeRenal Fanconi Syndromes and Other Proximal Tubular DisordersOrganic solventsPediatric Fanconi SyndromeClinical Syndromes of Metabolic AcidosisThe role of taurine in renal disordersClinical presentation and management in acute toluene intoxication: a case seriesOccupational Exposure to Paints Causes Impairment of Kidney FunctionsRenal Manifestations of Recreational Drug UseNephrotoxicity of Lithium and Drugs of AbuseFanconi SyndromeDRUGS OF ABUSESolventsVolatile solvent abuse caused glomerulopathy and tubulopathy in street childrenFanconi SyndromeClinical Syndromes of Metabolic AcidosisVolatile substances with special reference to volatile substance abuseMetabolic Acidosis and Renal Tubular Injury Due to Pure Toluene InhalationUrinary Calculi Associated with Solvent AbuseDrug AbuseShould the Urine PCO2 or the Rate of Excretion of Ammonium Be the Gold Standard to Diagnose Distal Renal Tubular Acidosis?Notice of Intended Changes—Toluene, Trimethylamine, and Vinyl AcetateParenchymal Diseases of the KidneysOliguric Acute Renal Failure due to Glue-SniffingVolatile Substances of AbuseMethanol poisoning as a result of inhalational solvent abuseUrinary levels of proteins and metabolites in workers exposed to tolueneSolventes de cola: abuso e efeitos nocivos à saúdeChronic Non-neurological Toxicity from Volatile Substance AbuseLetter to the EditorCOMPLICATIONS OF CHRONIC VOLATILE SUBSTANCE ABUSEROUTINE VAGINAL EXAMINATION AT ANTENATAL BOOKINGAcute Renal Failure Due to Interstitial Nephritis Induced by 'Glue-Sniffing' with Subsequent RecoveryToluene"Schnüffelstoffe"Anti-glomerular basement membrane antibody-mediated glomerulonephritis due to glue sniffingInhalant use among American Indian youthSerum electrolyte abnormalities caused by drugsRenal Disease Associated with Toluene InhalationRenal Effects of Acute Exposure to TolueneCOMPLICATIONS OF CHRONIC GLUE (TOLUENE) ABUSE IN ADOLESCENTSPersistent visual hallucinations secondary to chronic solvent encephalopathy: case report and review of the literatureNeurological Sequelae of Toluene AbuseLiteraturSolvent Abuse: A Shift to AdultsSyndromes of Toluene Sniffing in AdultsHOWARD Z. STREICHER, M.D., PATRICIA A. GABOW, M.D., ALVIN H. MOSS, M.D., DWIGHT KONO, M.D., WILLIAM D. KAEHNY, M.D. 1 January 1980Volume 92, Issue 1Page: 69-70KeywordsAcidosisAtaxiaDrugsHeartInhalationProteinuriaToxicity Issue Published: 1 January 1980 Copyright©1980 American College of PhysiciansPDF DownloadLoading ...