Novel dithiocarbamate carbapenems with anti-MRSA activity

Role of an altered penicillin-binding protein in methicillin- and cephem-resistant Staphylococcus aureus

Yukio Utsui, Takeshi Yokota · Antimicrobial Agents and Chemotherapy · 1985 · 363 citations · Full text

Antimicrobial Resistance Gene, Antimicrobial Susceptibility, Health Sciences +14

Synthetic Carbapenem Antibiotics. I. 1-b-Methylcarbapenem

L. D. Cama, David H. Shih, Florence Baker et al. · Heterocycles · 1984 · 198 citations · Full text

Medicinal Chemistry, Antimicrobial Drug Discovery, Biochemistry +15

Structural Features Resulting in Convulsive Activity of Carbapenem Compounds: Effect of C-2 Side Chain.

Yoshihiro Sumita, HIROSHI NOUDA · The Journal of Antibiotics · 1995 · 75 citations · Full text

Therapeutic efficacy of BO-3482, a novel dithiocarbamate carbapenem, in mice infected with methicillin-resistant Staphylococcus aureus

R Nagano, Kenji Shibata, Toshio Naito et al. · Antimicrobial Agents and Chemotherapy · 1997 · 43 citations · Full text

Mrsa Septicemia Model, Novel Dithiocarbamate Carbapenem, Pharmacotherapy +20

Discovery and structure-activity relationship of a series of 1-carba-1-dethiacephems exhibiting activity against methicillin-resistant Staphylococcus aureus

Robert J. Ternansky, Susan E. Draheim, Andrew Pike et al. · Journal of Medicinal Chemistry · 1993 · 41 citations

Antimicrobial Chemotherapy, Pharmaceutical Chemistry, Drug Resistance +17