Escherichia coli isolated from a Crohn's disease patient adheres, invades, and induces inflammatory responses in polarized intestinal epithelial cells

CX ₃ CR1-Mediated Dendritic Cell Access to the Intestinal Lumen and Bacterial Clearance

Jan Hendrik Niess, Stephan Brand, Xiubin Gu et al. · Science · 2005 · 1.6K citations

Specialized Dcs, Innate Immune System, Immunology +18

High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease

Arlette Darfeuille–Michaud, Jérôme Boudeau, P. Bulois et al. · Gastroenterology · 2004 · 1.5K citations · Full text

Mucosal Immunology, Ileal Mucosa, Gastroenterology +9

Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease

Arlette Darfeuille–Michaud, Christel Neut, Nicolas Barnich et al. · Gastroenterology · 1998 · 856 citations

Ileal Mucosa, Gastroenterology, Traveler Diarrhea +7

Complete atomic model of the bacterial flagellar filament by electron cryomicroscopy

Koji Yonekura, Saori Maki-Yonekura, Keiichi Namba · Nature · 2003 · 748 citations

Electron Cryomicroscopy, Prokaryotic System, Microscopy +8

Enhanced Escherichia coli adherence and invasion in Crohn’s disease and colon cancer 1 1The authors thank Professor T. K. Korhonen (Division of General Microbiology, University of Helsinki, Finland), who kindly donated Escherichia coli IH11165; Professor J.-F. Colombel (Laboratoire de Recherche sur les Maladies Inflammatoire de l’Intestine, Centre Hospitalier Universitaire, Lille, France) and Professor A. Darfeuille-Michaud (Faculte de Pharmacie, Clermont-Ferrand, France), who kindly donated the Crohn’s disease ileal isolates LF10 and LF82; and Dr. Keith Leiper (Gastroenterology Unit, Royal Liverpool & Broadgreen University Hospitals Trust, Liverpool, UK) for his cooperation in obtaining colorectal tissue specimens.As a consequence of the work described herein, a patent application has been filed by the University of Liverpool regarding the use of soluble plantain fiber in Crohn’s disease.

Helen Martin, Barry J. Campbell, C. Anthony Hart et al. · Gastroenterology · 2004 · 707 citations · Full text