Concepedia

Rapid and practical synthesis of (−)-1-deoxyaltronojirimycin

Oskari K. Karjalainen, Ari M. P. Koskinen

Organic & Biomolecular Chemistry · 2010 · 25 citations · 32 references

DOI

Concepts

Abstract

Herein a practical and scalable route to 1-deoxyaltronojirimycin is presented. The target is achieved in 9 steps and 43% yield featuring only two chromatographic purifications.

References

32

An improved catalytic OsO4 oxidation of olefins to -1,2-glycols using tertiary amine oxides as the oxidant

V. VanRheenen, Robert C. Kelly · Tetrahedron Letters · 1976 · 1K citations

, , +10

A Versatile and Highly Selective Hypervalent Iodine (III)/2,2,6,6-Tetramethyl-1-piperidinyloxyl-Mediated Oxidation of Alcohols to Carbonyl Compounds

A. DE MICO, Roberto Margarita, Luca Parlanti et al. · The Journal of Organic Chemistry · 1997 · 763 citations

, , +8

Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis

Timothy M. Cox, Robin Lachmann, C. E. Hollak et al. · The Lancet · 2000 · 744 citations

, , +4

Iminosugars-From Synthesis to Therapeutic Applications

Vasant Ranade · American Journal of Therapeutics · 2008 · 329 citations

, , +3

Osmium-Catalyzed Dihydroxylation of Olefins in Acidic Media: Old Process, New Tricks

Philippe Dupau, Robert Epple, Allen A. Thomas et al. · Advanced Synthesis & Catalysis · 2002 · 244 citations

, , +6