Zirconium-Catalyzed Oxidation of Primary Aliphatic Amines to Nitro Compounds withtert-Butyl Hydroperoxide

Abstract

Primary aliphatic amines are oxidized with tert-butyl hydroperoxide to the corresponding nitro compounds in 50−98% yield using Zr(Ot-Bu)4 as the catalyst. The CH-acidic nitro compounds are not epimerized under these reaction conditions.