Impact of Glucose Intolerance and Insulin Resistance on Cardiac Structure and Function

Martin K. Rutter, Helen Parise, Emelia J. Benjamin, Daniel Levy, Martin G. Larson, James B. Meigs, Richard W. Nesto, Peter W.F. Wilson, Ramachandran S. Vasan

Circulation · 2003 · 502 citations · 26 references

Abstract

In our large community-based sample, LV mass and wall thickness increased with worsening glucose intolerance, an effect that was more striking in women compared with men. Insulin resistance was associated with increased LV mass in women alone, but this relation was largely accounted for by obesity.

References

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