Investigation of chalcones and benzochalcones as inhibitors of breast cancer resistance protein

The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)

Thomas Litman, Mariafiorella Brangi, Eric A. Hudson et al. · Journal of Cell Science · 2000 · 531 citations

Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein.

Sridhar K. Rabindran, D D Ross, L. Austin Doyle et al. · PubMed · 2000 · 490 citations

Breast Oncology, Multidrug Resistance, Antimicrobial Chemotherapy +16

The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells.

Min Kim, Hēth Turnquist, John D. Jackson et al. · PubMed · 2002 · 397 citations

Tumor Biology, Breast Cancer Resistance, Health Sciences +14

Antimalarial Alkoxylated and Hydroxylated Chalones:  Structure−Activity Relationship Analysis

Mei Liu, Prapon Wilairat, Mei‐Lin Go · Journal of Medicinal Chemistry · 2001 · 396 citations

Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells.

Robert W. Robey, W Y Medina-Pérez, Kenryu Nishiyama et al. · PubMed · 2001 · 342 citations

Chemoprevention Strategy, Atp-binding Cassette Half-transporter, Cancer Biology +16