Studies of organotin‐schiff base complexes as new potential amebicidal agents

Abstract

Some new organotin(IV) complexes of Schiff bases containing sulfur and fluorine were tested for their activity on axenically grown Entamoeba histolytica trophozoites (strain NIH‐20). Some of the complexes were found to be potentially active at low doses, and one compound, tri‐n‐butyltin (2‐fluorobcnzaldehyde‐S‐benzyldithiocarba‐zate), showed remarkable activity at an extremely low dose even after 48 h.