Genetic complementation after fusion of Tay-Sachs and Sandhoff cells

Tay-Sachs Disease: Generalized Absence of a Beta-D- <i>N</i> -Acetylhexosaminidase Component

Shintaro Okada, John S. O’Brien · Science · 1969 · 708 citations

Deficient hexosaminidase activity in an exceptional case of Tay-Sachs disease with additional storage of kidney globoside in visceral organs

Konrad Sandhoff, U. Andreae, Horst Jatzkewitz · Life Sciences · 1968 · 329 citations

Tay-sachs Disease, Exceptional Case, Immunology +3

Genetic Heterogeneity of Xeroderma Pigmentosum demonstrated by Somatic Cell Hybridization

E.A. de Weerd-Kastelein, W. Keijzer, D. Bootsma · Nature New Biology · 1972 · 320 citations

Somatic Variant, Hybridisation, Somatic Cell Genetics +8

Lysosomal hydrolases: Conversion of acidic to basic forms by neuraminidase

Alfred Goldstone, Harold Koenig · FEBS Letters · 1971 · 148 citations

Cellular Enzymology, Biochemistry, Natural Sciences +8

Poliovirus Replication and Cytopathogenicity in Monolayer Hamster Cell Cultures Fused with Beta Propiolactone-Inactivated Sendai Virus

J. M. Neff, John F. Enders · Experimental Biology and Medicine · 1968 · 116 citations

Monolayer Cultures, Cell-based Vaccine Production, Viral Replication +11