Serum Transaminase Activity in X-Irradiated Rabbits

Abstract

Rabbits were subjected to x-irradiation in dosages of 500, 750, and 1,000 r. Serum glutamic oxaloacetic transaminase estimations were accomplished at 3, 6, and 24 hours post-irradiation. A significant increase in G-O-T activity could be identified at 6 hours in the rabbit group subjected to 500 r, and as early as 3 hours post-irradiation in the 750 r and 1,000 r animal groups. For the latter animals, the noted increase at 6 hours served to segregate 75% of the group on an individual basis. In rabbits subjected to 625 r of x-irradiation no relation was found between the serum G-O-T elevation and survival time.