N‐acetylcysteine prevents loss of dopaminergic neurons in the <i>EAAC1</i>^−/− mouse

Abstract

These findings suggest that the EAAC1(-/-) mouse may be a useful model of the chronic neuronal oxidative stress that occurs in PD. The salutary effects of N-acetylcysteine in this mouse model provide an impetus for clinical evaluation of glutathione repletion in PD.