Organic Letters · 2012 · 111 citations · 78 references
Radical Initiator AibnChemical EngineeringCross-coupling ReactionEngineeringCatalytic AmountNatural SciencesDiversity-oriented SynthesisCatalytic SynthesisOrganic ChemistryTertiary AminesCatalysisOrganometallic CatalysisChemistryHeterocycle ChemistryOxidation ChemistryRedox ChemistryPrimary Amines
In the presence of a catalytic amount of radical initiator AIBN, primary amines are oxidatively coupled to imines and tertiary amines are cyanated to α-aminonitriles. These "metal-free" aerobic oxidative coupling reactions may find applications in a wide range of "green" oxidation chemistry.
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