Concepedia

Effects of Atorvastatin on Angiogenesis in Hindlimb Ischemia and Endothelial Progenitor Cell Formation in Rats

Mitsuyasu Matsumura, Noboru Fukuda, Naohiko Kobayashi, Hisaki Umezawa, Ayako Takasaka, Tarô Matsumoto, En‐Hui Yao, Takahiro Ueno, Nanao Negishi

Journal of Atherosclerosis and Thrombosis · 2009 · 54 citations · 29 references

DOIFull text

Open access

Abstract

Atorvastatin strongly induced angiogenesis with increases in angiogenic cytokines, HO-1 and EPC numbers. Statins are thus considered potertial agents for therapeutic angiogenesis.

References

29

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Takayuki Asahara, Toyoaki Murohara, Alison Sullivan et al. · Science · 1997 · 8.7K citations

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Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial—Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial

Peter Sever, Björn Dahlöf, Neil R Poulter et al. · The Lancet · 2003 · 3.8K citations

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Circulating Endothelial Progenitor Cells, Vascular Function, and Cardiovascular Risk

Jonathan Hill, Gloria Zalos, Julian Halcox et al. · New England Journal of Medicine · 2003 · 3.4K citations

Bone Marrow Origin of Endothelial Progenitor Cells Responsible for Postnatal Vasculogenesis in Physiological and Pathological Neovascularization

Takayuki Asahara, Haruchika Masuda, Tomono Takahashi et al. · Circulation Research · 1999 · 3.2K citations · Full text

Number and Migratory Activity of Circulating Endothelial Progenitor Cells Inversely Correlate With Risk Factors for Coronary Artery Disease

Mariuca Vasa, Stephan Fichtlscherer, Alexandra Aicher et al. · Circulation Research · 2001 · 2.3K citations · Full text