Continuous Intravenous Infusion of Rocuronium (ORG 9426) in Patients Receiving Balanced, Enflurane, or Isoflurane Anesthesia

Abstract

The infusion requirements to maintain 95% twitch depression approximated 10 micrograms.kg-1.min-1 during barbiturate-nitrous oxide-opioid anesthesia. These requirements were reduced by 40% during anesthesia involving enflurane or isoflurane.