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Inhibition of γ-secretase activity reduces Aβ production, reduces oxidative stress, increases mitochondrial activity and leads to reduced vulnerability to apoptosis: Implications for the treatment of Alzheimer's disease

Neurodegenerative DiseasesAlzheimer's DiseaseMitochondrial FunctionBiochemistryMitochondrial ActivityMedicineCell DeathDegenerative PathologyNeuroprotectionAging-associated DiseaseReduces Oxidative StressMetabolismPharmacologyOxidative StressProtective Mechanisms