Holmium-166 radioembolization for the treatment of patients with liver metastases: design of the phase I HEPAR trial - Concepedia

Concepedia

Publication | Open Access

Holmium-166 radioembolization for the treatment of patients with liver metastases: design of the phase I HEPAR trial

DOI Full Paper Access

112

Citations

25

References

2010

Year

Maarten LJ Smits, J. Frank W. Nijsen, Maurice AAJ van den Bosch, Marnix G. E. H. Lam, M. A. D. Vente, Julia E. Huijbregts, Alfred D. van het Schip, Mattijs Elschot, Wouter Bult, Hugo WAM de Jong,

Journal of Experimental & Clinical Cancer Research

Abstract

This will be the first clinical study on 166Ho-RE. Based on preclinical studies, it is expected that 166Ho-RE has a safety and toxicity profile comparable to that of 90Y-RE. The biochemical and radionuclide characteristics of 166Ho-PLLA-MS that enable accurate dosimetry calculations and biodistribution assessment may however improve the overall safety of the procedure.

References

	Year	Citations

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