PS II inhibitory activity of 2,4-diamino-6-chloro-s-triazines with a chiral sec-butyl and/or .ALPHA.-methylbenzyl group.

Abstract

The influence of steric factors on the activity of chiral isomers on the A^-a-methylbenzyl and/or NA-sec-bntyl group of the 2,4-diamino-6-chloro-5-triazines as the inhibitor of the Hill reaction was examined. The (5)-isomers for either chiral center were more active than the corresponding (/?)isomers. The A^-( The level of optical discrimination of the receptor site for the chiral isomer of the a-methylbenzyl-s-triazines was greater than those for the sec-butyl derivatives, and their rates varied with the change of steric hindrance of the substituent at the other aminogroup.