Stanniocalcin 1 Prevents Cytosolic Ca2+ Overload and Cell Hypercontracture in Cardiomyocytes

Abstract

STC1 prevented the increase in diastolic Ca(2+) overload and ouabain-induced cell hypercontracture, which suggests that STC1 could effectively prevent cytosolic Ca(2+) overload and protect cardiomyocytes from pathophysiological conditions such as in the failing heart.