Preparative purification of supercoiled plasmid DNA using anion-exchange chromatography

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

H.C. Birnboim, Janine Doly · Nucleic Acids Research · 1979 · 14.9K citations · Full text

Life Sciences, Genetics, Molecular Biology +11

Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans.

Gary J. Nabel, E G Nabel, Zhiyong Yang et al. · Proceedings of the National Academy of Sciences · 1993 · 890 citations

Medicine, Biotechnology, Oncology +17

Structure of plectonemically supercoiled DNA

T. Christian Boles, James H. White, Nicholas R. Cozzarelli · Journal of Molecular Biology · 1990 · 397 citations

Life Sciences, Biochemistry, Molecular Biology +6

Conformational and thermodynamic properties of supercoiled DNA

Alexander V. Vologodskii, Stephen D. Levene, Konstantin V. Klenin et al. · Journal of Molecular Biology · 1992 · 387 citations

Life Sciences, Genetics, Molecular Biology +17

Cancer Gene Therapy Using Plasmid DNA: Purification of DNA for Human Clinical Trials

Nancy A. Horn, Jennifer Meek, Gregg Budahazi et al. · Human Gene Therapy · 1995 · 244 citations

Life Sciences, Biotechnology, Pharmaceutical Biotechnology +17