Both bone marrow‐derived and non‐bone marrow‐derived cells contribute to <scp>AIM</scp>2 and <scp>NLRP</scp>3 inflammasome activation in a MyD88‐dependent manner in dietary steatohepatitis

Abstract

Our data demonstrate that both bone marrow-derived and non-BM-derived cells contribute to inflammasome activation in a MyD88-dependent manner in dietary steatohepatitis. We show that AIM2 inflammasome expression and activation are further augmented by TLR9 ligands in dietary steatohepatitis.