SYSTEMIC AND RENAL CIRCULATORY CHANGES FOLLOWING THE ADMINISTRATION OF ADRENIN, EPHEDRINE, AND PAREDRINOL TO NORMAL MAN

Abstract

This report concerns the systemic and renal circulatory changes in normal man during the action of adrenin, ephedrine, and paredrinol. Special attention has been paid to the interrela- tionship and integration of the many factors in- volved in the production of the over-all response. Although these three substances are similar chemi- cally and have long been known (1) as vaso- pressor drugs, their sites and modes of action appear to vary. The observations presented here throw light upon the circulatory mechanisms in- volved in the pressor response.