Hypoxia-inducible proto-oncogene Pim-1 is a prognostic marker in pancreatic ductal adenocarcinoma - Concepedia

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Hypoxia-inducible proto-oncogene Pim-1 is a prognostic marker in pancreatic ductal adenocarcinoma

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References

2008

Year

Carolin Reiser–Erkan, Mert Erkan, Pan Zheng, Sándor Békási, Nathalia A. Giese, Sylvia Streit, Christoph Michalski, Helmut Friess, Jörg Kleeff

Cancer Biology & Therapy

Abstract

Hypoxia is a novel inducer of Pim-1 expression. Compared to non-malignant tissues Pim-1 significantly increases in pancreatic cancer. However, the presence of Pim-1 in cancer cells has a positive prognostic impact.