TAME‐Hex A − A Novel Bifunctional Chelating Agent for Radioimmunoimaging

Abstract

Abstract Two novel (bifunctional) chelating agents, TAME‐Hex A and B, which are polyaminopolycarboxylic acids based on the tripodal TAME [tris(aminomethyl)ethane] structure, have been designed and synthesized. The chelators show very good stability with gallium( III ) ions and thus are highly effective candidates for use in radioimmunoimaging (RII), especially in positron emission tomography (PET). (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)