LIMITATIONS OF BIOPSY GLEASON GRADE: IMPLICATIONS FOR COUNSELING PATIENTS WITH BIOPSY GLEASON SCORE 6 PROSTATE CANCER

Abstract

Gleason grade on needle biopsy is an inexact predictor of the final grade following radical prostatectomy. Patients with biopsy Gleason score 6 who are under graded are at significantly higher risk for adverse pathological features and biochemical recurrence than patients who remain with Gleason score 6 or less on final pathology findings.