Sitafloxacin Activity against <i>Helicobacter pylori</i> Isolates, Including Those with <i>gyrA</i> Mutations

Abstract

Sitafloxacin showed MICs of less than or equal to 0.5 microg/ml against 105 isolates of Helicobacter pylori, including 44 isolates with mutations in the gyrA gene. The highest MICs for garenoxacin and levofloxacin were 8 and 64 times, respectively, higher than the highest MICs observed for sitafloxacin.