PubMed · 1983 · 50 citations · 0 references
MedicineOncologyPharmacotherapyBreast OncologyChemotherapyMetastasisBreast Cancer OncologyBreast Cancer PharmacotherapyClinical Trials In OncologyCombination ChemotherapyMetastatic Breast CancerMetastatic Cancer ManagementBreast Cancer ChemotherapyChemotherapy Regimen DesignEastern Cooperative Oncology Group Performance StatusMetastatic Breast Cancer TreatmentSequencing With Chemotherapy
The concepts involved in fixed sequencing of chemotherapy and of adding prednisone to CMF were tested by the ECOG from October 1975 to June 1978. From October 1975 to October 1976, 144 previously untreated evaluable patients with metastatic breast cancer were randomized to receive: 1) CMF—47;2) CMFP