Oestrogen Receptor-Mediated Modulation of the EGFR/MAPK Pathway in Tamoxifen-Resistant MCF-7 Cells

Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase

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Life Sciences, Biochemistry, Molecular Biology +17

Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation.

Giuseppe Bunone, P. A. Briand, Richard J. Miksicek et al. · The EMBO Journal · 1996 · 989 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Estrogen-dependent, tamoxifen-resistant tumorigenic growth of MCF-7 cells transfected with HER2/neu

Christopher C. Benz, Gary K. Scott, Jay Sarup et al. · Breast Cancer Research and Treatment · 1992 · 760 citations

Medicine, Cancer Biology, Oncology +14

Fulvestrant, Formerly ICI 182,780, Is as Effective as Anastrozole in Postmenopausal Women With Advanced Breast Cancer Progressing After Prior Endocrine Treatment

Anthony Howell, J.F.R. Robertson, J. Albano et al. · Journal of Clinical Oncology · 2002 · 669 citations

Medicine, Oncology, Pharmacology +14

Tamoxifen activation of the estrogen receptor/AP-1 pathway: potential origin for the cell-specific estrogen-like effects of antiestrogens.

Paul Webb, Gabriela N. Lopez, Rosalie M. Uht et al. · Molecular Endocrinology · 1995 · 663 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14