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Design, synthesis, biological evaluation and molecular modeling of dihydropyrazole sulfonamide derivatives as potential COX-1/COX-2 inhibitors

Combinatorial ChemistryMedicinal ChemistryBioorganic ChemistryBiochemistryNatural SciencesMedicineRational Drug DesignDihydropyrazole Sulfonamide DerivativesAnti-cancer AgentDrug DevelopmentPharmacologyMolecular ModelingDrug DiscoveryPotential Cox-1/cox-2 Inhibitors