Movement Disorders · 2007 · 204 citations · 6 references
MedicineNeurosurgerySurgeryAnesthesiaCerebrovascular SurgeryClinical NeuroscienceDeep Brain StimulationMultiple SclerosisNeurostimulationParkinson Disease SurgeryComplication Rate AnalysisDeep Brain Stimulation ComplicationsMorbidity Rate AnalysisStimulation-induced Side EffectsSurgical Site Morbidity
Serious adverse events (SAEs) during the first 30 postoperative days after stereotactic surgery for Deep-Brain-Stimulation performed in 1,183 patients were retrospectively collected from five German stereotactic centers. The mortality rate was 0.4% and causes for death were pneumonia, pulmonary embolism, hepatopathy, and a case of complicated multiple sclerosis. The permanent surgical morbidity rate was 1%. The most frequently observed SAEs were intracranial hemorrhage (2.2%) and pneumonia (0.6%). Skin infection occurred in 5 of 1,183 patients (0.4%). Surgical complications caused secondary AEs (e.g. pneumonia) preferentially in older patients and in patients treated for Parkinson's disease (PD). Complication rates did not differ among the five centers.
6
A Randomized Trial of Deep-Brain Stimulation for Parkinson's Disease
Günther Deuschl, Carmen Schade‐Brittinger, Paul Krack et al. · New England Journal of Medicine · 2006 · 2.9K citations · Full text
Medicine, Neurology, Neuroscience +17
Long-term Hardware-related Complications of Deep Brain Stimulation
Michael Oh, Aviva Abosch, Seong‐Hyop Kim et al. · Neurosurgery · 2002 · 396 citations
Surgical and hardware complications of subthalamic stimulation
Kelly E. Lyons, Steven B. Wilkinson, John Overman et al. · Neurology · 2004 · 272 citations