Science · 1978 · 376 citations · 9 references
Natural SciencesBiochemistryChemistryGeochemistrySoil BiogeochemistrySoil ChemistryAmino Acid ChemistryAmino Acid ProductionChemical EvolutionClay MineralogyPeptide ChemistryPrebiotic ChemistryAmino Acid GeochemistryAmino AcidsChemical Evolution ModelingMechanism Of Peptide Bond FormationPrebiotic Earth ConditionsPrebiotic Synthesis Of Amino AcidsThermal FluctuationsWater Content Variation
As geologically relevant models of prebiotic environments, systems consisting of clay, water, and amino acids were subjected to cyclic variations in temperature and water content. Fluctuations of both variables produced longer oligopeptides in higher yields than were produced by temperature fluctuations alone. The results suggest that fluctuating environments provided a favorable geological setting in which the rate and extent of chemical evolution would have been determined by the number and frequency of cycles.
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Thermal Polyamino Acids: Synthesis at Less Than 100°C
Duane L. Rohlfing · Science · 1976 · 74 citations
Peptide Formation mediated by Cyanate
José Juan Alvarado Flores, James O. Leckie · Nature · 1973 · 36 citations