Soluble vascular endothelial growth factor receptor-1 (sFlt-1) is increased throughout gestation in patients who have preeclampsia develop

Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

Sharon E. Maynard, Jiang-Yong Min, Jaime R. Merchan et al. · Journal of Clinical Investigation · 2003 · 4K citations · Full text

Medicine, Maternal Health, Obstetrics +17

Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor.

R.L. Kendall, Kenneth A. Thomas · Proceedings of the National Academy of Sciences · 1993 · 1.4K citations

Life Sciences, Molecular Biology, Cell Signaling +13

Pre-eclampsia: more than pregnancy-induced hypertension

James M. Roberts, Christopher W.G. Redman · The Lancet · 1993 · 1.3K citations

Medicine, Gynecology, Obstetrics +12

Vascular Endothelial Growth Factor Ligands and Receptors That Regulate Human Cytotrophoblast Survival Are Dysregulated in Severe Preeclampsia and Hemolysis, Elevated Liver Enzymes, and Low Platelets Syndrome

Yan Zhou, Michael McMaster, Kirstin Woo et al. · American Journal Of Pathology · 2002 · 644 citations · Full text

Public Health, Maternal Health, Obstetrics +17

Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate

Corey K. Goldman, Richard Kendall, Gustavo Cabrera et al. · Proceedings of the National Academy of Sciences · 1998 · 446 citations

Medicine, Cancer Biology, Oncology +16