The effect of ketamine on intraspinal acetylcholine release: Involvement of spinal nicotinic receptors

Norketamine, the main metabolite of ketamine, is a non-competitive NMDA receptor antagonist in the rat cortex and spinal cord

Bjarke Ebert, Søren Mikkelsen, Christian Thorkildsen et al. · European Journal of Pharmacology · 1997 · 266 citations

Life Sciences, Neurobiology, Neuroscience +14

Antinociceptive effects of intrathecally injected cholinomimetic drugs in the rat and cat

Tony L. Yaksh, Ris Dirksen, Gail J. Harty · European Journal of Pharmacology · 1985 · 256 citations

Medicine, Pharmacology, Neuropharmacology +10

Interaction of the Chiral Forms of Ketamine with Opioid, Phencyclidine, σ and Muscarinic Receptors

Olav Hustveit, A Maurset, Ivar Øye · Pharmacology & Toxicology · 1995 · 252 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Measurement of Acetylcholine Release in Freely Moving Rats by Means of Automated Intracerebral Dialysis

G. Damsma, B.H.C. Westerink, Jan B de Vries et al. · Journal of Neurochemistry · 1987 · 214 citations

Medicine, Neuroscience, Pharmacology +12

Comparative pharmacology of the optical isomers of ketamine in mice

Susan Ryder, Walter L. Way, Anthony J. Trevor · European Journal of Pharmacology · 1978 · 197 citations

Medicine, Pharmacokinetics, Pharmacology +6