Total apolipoprotein E levels and specific isoform composition in cerebrospinal fluid and plasma from Alzheimer’s disease patients and controls

Clinical diagnosis of Alzheimer's disease

Guy M. McKhann, David A. Drachman, Marshall Folstein et al. · Neurology · 1984 · 28K citations · Full text

Medicine, Geriatric Medicine, Neurology +16

Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI.

D.T. Vernier · Journal of Lipid Research · 1990 · 3K citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

Elizabeth H. Corder, Ann M. Saunders, Neil Risch et al. · Nature Genetics · 1994 · 1.9K citations

Medicine, Genetics, Neurology +16

Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Aβ ₄₂ in humans

Anne M. Fagan, Mark A. Mintun, Robert H. Mach et al. · Annals of Neurology · 2005 · 1.3K citations

Life Sciences, Neurology, Neuroscience +16

Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance

Joseph M. Castellano, Jungsu Kim, Floy R. Stewart et al. · Science Translational Medicine · 2011 · 1.2K citations

Life Sciences, Neurobiology, Neuroscience +9