Concepedia

Nitroolefin-based coumarin as a colorimetric and fluorescent dual probe for biothiols

Yuanqiang Sun, Maliang Chen, Jing Liu, Xin Lv, Junfei Li, Wei Guo

Chemical Communications · 2011 · 156 citations · 39 references

DOI

Concepts

Abstract

A coumarin-based thiol probe featuring the 1,4-addition reaction of thiols to nitroolefin was reported. The molecular probe exhibited higher selectivity toward biothiols (Cys, Hcy and GSH) than other amino acids.

References

39

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Detection of Homocysteine and Cysteine

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Visual Detection of Cysteine and Homocysteine

Oleksandr Rusin, Nadia N. St. Luce, Rezik A. Agbaria et al. · Journal of the American Chemical Society · 2003 · 515 citations

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A Rhodamine-Based Fluorescent Probe Containing a Se−N Bond for Detecting Thiols and Its Application in Living Cells

Bo Tang, Yanlong Xing, Ping Li et al. · Journal of the American Chemical Society · 2007 · 411 citations

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2,4‐Dinitrobenzenesulfonyl Fluoresceins as Fluorescent Alternatives to Ellman's Reagent in Thiol‐Quantification Enzyme Assays

Hatsuo Maeda, Hiromi Matsuno, Mai Ushida et al. · Angewandte Chemie International Edition · 2005 · 392 citations · Full text

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