Dual targeting of IGF-1R and PDGFR inhibits proliferation in high-grade gliomas cells and induces radiosensitivity in JNK-1 expressing cells

Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops.

Monica Hermanson, Lena Claesson‐Welsh, Carl‐Henrik Heldin et al. · PubMed · 1992 · 701 citations

Medicine, Oncology, Pathology +15

Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation.

Michael Kaleko, William J. Rutter, A. Dusty Miller · Molecular and Cellular Biology · 1990 · 399 citations · Full text

Medicine, Cell Biology, Oncology +17

The effect of ionizing radiation on signal transduction: antibodies to EGF receptor sensitize A431 cells to radiation

Naomi Balaban, Janaki Moni, Mary Shannon et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 1996 · 148 citations

Medicine, Cell Biology, Oncology +14

Dominant negative EGFR-CD533 and inhibition of MAPK modify JNK1 activation and enhance radiation toxicity of human mammary carcinoma cells

Dean B. Reardon, Joseph N. Contessa, Ross B. Mikkelsen et al. · Oncogene · 1999 · 133 citations

Medicine, Cell Biology, Oncology +16

Molecular neuro-oncology and development of targeted therapeutic strategies for brain tumors

NewtonHB · 中国神经肿瘤杂志 · 2004 · 103 citations

Medicine, Neuroscience, Oncology +16