Gene frequencies of the HNA‐4a and ‐5a neutrophil antigens in Brazilian persons and a new polymerase chain reaction‐restriction fragment length polymorphism method for HNA‐5a genotyping

Abstract

Comparing to another populations, Brazilians present a higher frequency of HNA-4a-negative allele, suggesting that Brazilians would be more susceptible to HNA-4a alloimmunization. Moreover, the distribution of the HNA-4 alleles observed in Amazon Indians is quite similar to that reported among Koreans. Besides that, a new effective and efficient HNA-5a genotyping technique is now available for population studies.