Antagonism of the effects of the hallucinogen dom and the purported 5-HT agonist quipazine by 5-HT2 antagonists

A SIMPLIFIED METHOD OF EVALUATING DOSE-EFFECT EXPERIMENTS

J.T. LITCHFIELD, Frank Wilcoxon · Journal of Pharmacology and Experimental Therapeutics · 1949 · 7.3K citations

Public Health, Biostatistics, Pharmacology +12

Multiple Serotonin Receptors: Differential Binding of [3H]5-Hydroxytryptamine, [3H]Lysergic Acid Diethylamide and [3H]Spiroperidol

Stephen J. Peroutka, Solomon H. Snyder · Molecular Pharmacology · 1979 · 1.4K citations

Medicine, Neuroscience, Pharmacology +15

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

J E Leysen, C. J. E. Niemegeers, Jan M. Van Nueten et al. · Molecular Pharmacology · 1982 · 1.1K citations

Medicine, Medicinal Chemistry, Pharmacology +17

Receptor binding profile of R 41 468, A novel antagonist at 5-HT2 receptors

J.E. Leysen, F. Awouters, Ludo Kennis et al. · Life Sciences · 1981 · 846 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Two Distinct Central Serotonin Receptors with Different Physiological Functions

Stephen J. Peroutka, Richard M. Lebovitz, Solomon H. Snyder · Science · 1981 · 637 citations

Medicine, Neuroscience, Pharmacology +17