Concepedia

Palladium catalysed addition of masked formyl cyanides ROCH(CN)2 to aldehydes

Hisao Nemoto, Yasufumi Kubota, Yoshinori Yamamoto

Journal of the Chemical Society Chemical Communications · 1994 · 17 citations · 5 references

DOI

Concepts

Abstract

The palladium catalysed reactions of masked formyl cyanides 1 with aldehydes 2, followed by treatment with either diketene or acetic anhydride–pyridine, afford the addition products protected with acetylacetate 5 or acetyl group 6, respectively.

References

5

Synthesis of .eta.1 oxygen-bound rhodium enolates. Applications to catalytic aldol chemistry

Greg A. Slough, Robert G. Bergman, Clayton H. Heathcock · Journal of the American Chemical Society · 1989 · 177 citations

, , +5

Ruthenium-catalyzed aldol and Michael reactions of activated nitriles

Takeshi Naota, Hiroshi Taki, Masahiko Mizuno et al. · Journal of the American Chemical Society · 1989 · 143 citations

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Development of a new acyl anion equivalent for the preparation of masked activated esters, and their use to prepare a dipeptide

Hisao Nemoto, Yasufumi Kubota, Yoshinori Yamamoto · The Journal of Organic Chemistry · 1990 · 104 citations

, , +7

Transition Metal Catalyzed Addition of Certain Nucleophiles to Imines

Yoshinori Yamamoto, Yasufumi Kubota, Yoshihiro Honda et al. · Journal of the American Chemical Society · 1994 · 55 citations

, , +10

Synthesis of 1,4-dicarbonyl compounds via the conjugate addition of a masked activated ester, ROCH(CN)2

Yasufumi Kubota, Hisao Nemoto, Yoshinori Yamamoto · The Journal of Organic Chemistry · 1991 · 30 citations

, , +5