c-Src modulates ErbB2 and ErbB3 heterocomplex formation and function

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene

Dennis J. Slamon, Gary M. Clark, Steven Wong et al. · Science · 1987 · 11.7K citations

Medicine, Genetics, Oncology +14

A Hierarchical Network of Interreceptor Interactions Determines Signal Transduction by Neu Differentiation Factor/Neuregulin and Epidermal Growth Factor

Eldad Tzahar, Hadassa Waterman, Xiomei Chen et al. · Molecular and Cellular Biology · 1996 · 1K citations · Full text

Life Sciences, Molecular Biology, Oncology +17

<i>erb</i> B-2 Is a Potent Oncogene When Overexpressed in NIH/3T3 Cells

Pier Paolo Di Fiore, Jacalyn H. Pierce, Matthias H. Kraus et al. · Science · 1987 · 1K citations

Medicine, Molecular Biology, Oncology +14

The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation

Thomas Holbro, Roger R. Beerli, Francisca Maurer et al. · Proceedings of the National Academy of Sciences · 2003 · 960 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Crystal Structures of c-Src Reveal Features of Its Autoinhibitory Mechanism

Wenqing Xu, Amish Doshi, Ming Lei et al. · Molecular Cell · 1999 · 874 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16