The nicotinic antagonist mecamylamine precipitates nicotine abstinence syndrome in the rat

Smoking withdrawal symptoms in two weeks of abstinence

Saul Shiffman, Murray E. Jarvik · Psychopharmacology · 1976 · 547 citations

Tobacco Cessation, Tobacco Control, Substance Abuse +10

The effects of nicotine on locomotor activity in non‐tolerant and tolerant rats

Paul B. S. Clarke, Ramesh Kumar · British Journal of Pharmacology · 1983 · 458 citations · Full text

Symptoms of Tobacco Withdrawal

John Hughes · Archives of General Psychiatry · 1991 · 442 citations

Rodent model of nicotine abstinence syndrome

David H. Malin, John R. Lake, Paige Newlin-Maultsby et al. · Pharmacology Biochemistry and Behavior · 1992 · 334 citations

Tobacco Control, Substance Abuse, Behavioral Neuroscience +9

Characterization of nicotine binding in mouse brain and comparison with the binding of alpha-bungarotoxin and quinuclidinyl benzilate.

M J Marks, A C Collins · Molecular Pharmacology · 1982 · 310 citations